Thursday, December 3, 2020

Apparently, YES THEY CAN Vaccinate Us Through The Nasal Test Swabs And Target Our Brains!

 I am continuing my relentless assault on this entire scam-demic...Now with nearly 750 articles at this blog alone over the last 10+ months, I am continuing to discover even MORE valuable research that I definitely want everyone to be made aware of as the more and more I dig deeper down the 'rabbit hole' with this horrific crime against humanity, I begin to see that we are dealing with truly inhuman monsters bent on our very destruction..

Every day I have been posting my daily reports on the continuing fraud scam-demic situation here in Manitoba... The other day I could not help but notice in their 'official report' on how supposedly there have been over 355000 moronic Manitobans who have been stupid enough to fall for this horrific lie and went out and got themselves 'tested' at one of those idiotic and horrific 'PCR testing centers' across this province... 

I honestly have to shake my head in total disgust that these idiots do not even have a clue that they are going to those fraudulent sites and allowing fucking morons to insert 6 inch long sticks up their noses that not only can rupture the back of the nasal passageway which could eventually lead to brain damage, but are putting their lives into the hands of these criminal fucks who will gleefully apply their fraud 'PCR test' to the material collected from those swabs, and then proclaim FALSELY that some of the tests come back 'positive' for this fraudulent and still non-existent 'deadly virus'!

BUT it gets even better (or worse), for I want to present the following very important report that comes from the "Tap News" website, where facts are presented that show that the fraud 'nasal swab tests' that these pricks are using on everyone world-wide may in all actuality be their method for 'vaccinating' all of us!!!!!  Here is that article in its entirety for everyone to see for themselves, and I do have my usual thoughts and comments to follow:

YES, THEY CAN VACCINATE US THROUGH NASAL TEST SWABS AND TARGET THE BRAIN

by Silviu “Silview” Costinescu_

I don’t know if they do it, because no independent researchers examine those swabs, but I have always pointed out that our overlords seem more concerned with testing than with vaccinating. Almost like the vaccines were the bait and tests were the switch. And now we also know they totally CAN do that.
Just follow the science below.

November 3, 2020

RESEARCHERS ENGINEER TINY MACHINES THAT DELIVER MEDICINE EFFICIENTLY

by Johns Hopkins University School of Medicine


Johns Hopkins Researchers engineer tiny machines that deliver medicine efficiently
A theragripper is about the size of a speck of dust. This swab contains dozens of the tiny devices. Credit: Johns Hopkins University.

Inspired by a parasitic worm that digs its sharp teeth into its host’s intestines, Johns Hopkins researchers have designed tiny, star-shaped microdevices that can latch onto intestinal mucosa and release drugs into the body.

David Gracias, Ph.D., a professor in the Johns Hopkins University Whiting School of Engineering, and Johns Hopkins gastroenterologist Florin M. Selaru, M.D., director of the Johns Hopkins Inflammatory Bowel Disease Center, led a team of researchers and biomedical engineers that designed and tested shape-changing microdevices that mimic the way the parasitic hookworm affixes itself to an organism’s intestines.

Made of metal and thin, shape-changing film and coated in a heat-sensitive paraffin wax, “theragrippers,” each roughly the size of a dust speck, potentially can carry any drug and release it gradually into the body.

The team published results of an animal study this week as the cover article in the journal Science Advances.

Gradual or extended release of a drug is a long-sought goal in medicine. Selaru explains that a problem with extended-release drugs is they often make their way entirely through the gastrointestinal tract before they’ve finished dispensing their medication.

“Normal constriction and relaxation of GI tract muscles make it impossible for extended-release drugs to stay in the intestine long enough for the patient to receive the full dose,” says Selaru, who has collaborated with Gracias for more than 10 years. “We’ve been working to solve this problem by designing these small drug carriers that can autonomously latch onto the intestinal mucosa and keep the drug load inside the GI tract for a desired duration of time.”

Researchers engineer tiny machines that deliver medicine efficiently
When an open theragripper, left, is exposed to internal body temperatures, it closes on the instestinal wall. In the gripper’s center is a space for a small dose of a drug. Credit: Johns Hopkins University

Thousands of theragrippers can be deployed in the GI tract. When the paraffin wax coating on the grippers reaches the temperature inside the body, the devices close autonomously and clamp onto the colonic wall. The closing action causes the tiny, six-pointed devices to dig into the mucosa and remain attached to the colon, where they are retained and release their medicine payloads gradually into the body. Eventually, the theragrippers lose their hold on the tissue and are cleared from the intestine via normal gastrointestinal muscular function.

Taken from the original research annexes

Gracias notes advances in the field of biomedical engineering in recent years.

“We have seen the introduction of dynamic, microfabricated smart devices that can be controlled by electrical or chemical signals,” he says. “But these grippers are so small that batteries, antennas and other components will not fit on them.”

Theragrippers, says Gracias, don’t rely on electricity, wireless signals or external controls. “Instead, they operate like small, compressed springs with a temperature-triggered coating on the devices that releases the stored energy autonomously at body temperature.”

The Johns Hopkins researchers fabricated the devices with about 6,000 theragrippers per 3-inch silicon wafer. In their animal experiments, they loaded a pain-relieving drug onto the grippers. The researchers’ studies found that the animals into which theragrippers were administered had higher concentrates of the pain reliever in their bloodstreams than did the control group. The drug stayed in the test subjects’ systems for nearly 12 hours versus two hours in the control group.

“Swarms of microscopic robots that can be injected”
Tell Melinda Gates we can inject robots these days.

 

PubMed, 2015 Jun 9.:

NANONEUROTHERAPEUTICS APPROACH INTENDED FOR DIRECT NOSE TO BRAIN DELIVERY

Shadab Md  1 Gulam Mustafa  2   3 Sanjula Baboota  3 Javed Ali  3 Affiliations Expand

ABSTRACT

Context: Brain disorders remain the world’s leading cause of disability, and account for more hospitalizations and prolonged care than almost all other diseases combined. The majority of drugs, proteins and peptides do not readily permeate into brain due to the presence of the blood-brain barrier (BBB), thus impeding treatment of these conditions.

Objective: Attention has turned to developing novel and effective delivery systems to provide good bioavailability in the brain.

Methods: Intranasal administration is a non-invasive method of drug delivery that may bypass the BBB, allowing therapeutic substances direct access to the brain. However, intranasal administration produces quite low drug concentrations in the brain due limited nasal mucosal permeability and the harsh nasal cavity environment. Pre-clinical studies using encapsulation of drugs in nanoparticulate systems improved the nose to brain targeting and bioavailability in brain. However, the toxic effects of nanoparticles on brain function are unknown.

Result and conclusion: This review highlights the understanding of several brain diseases and the important pathophysiological mechanisms involved. The review discusses the role of nanotherapeutics in treating brain disorders via nose to brain delivery, the mechanisms of drug absorption across nasal mucosa to the brain, strategies to overcome the blood brain barrier, nanoformulation strategies for enhanced brain targeting via nasal route and neurotoxicity issues of nanoparticles.

Epub 2013 Oct 16.

NANOEMULSION-BASED INTRANASAL DRUG DELIVERY SYSTEM OF SAQUINAVIR MESYLATE FOR BRAIN TARGETING

Hitendra S Mahajan  1 Milind S MahajanPankaj P NerkarAnshuman Agrawal Affiliations Expand

ABSTRACT

The central nervous system (CNS) is an immunological privileged sanctuary site-providing reservoir for HIV-1 virus. Current anti-HIV drugs, although effective in reducing plasma viral levels, cannot eradicate the virus completely from the body. The low permeability of anti-HIV drugs across the blood-brain barrier (BBB) leads to insufficient delivery. Therefore, developing a novel approaches enhancing the CNS delivery of anti-HIV drugs are required for the treatment of neuro-AIDS. The aim of this study was to develop intranasal nanoemulsion (NE) for enhanced bioavailability and CNS targeting of saquinavir mesylate (SQVM). SQVM is a protease inhibitor which is a poorly soluble drug widely used as antiretroviral drug, with oral bioavailability is about 4%. The spontaneous emulsification method was used to prepare drug-loaded o/w nanoemulsion, which was characterized by droplet size, zeta potential, pH, drug content. Moreover, ex-vivo permeation studies were performed using sheep nasal mucosa. The optimized NE showed a significant increase in drug permeation rate compared to the plain drug suspension (PDS). Cilia toxicity study on sheep nasal mucosa showed no significant adverse effect of SQVM-loaded NE. Results of in vivo biodistribution studies show higher drug concentration in brain after intranasal administration of NE than intravenous delivered PDS. The higher percentage of drug targeting efficiency (% DTE) and nose-to-brain drug direct transport percentage (% DTP) for optimized NE indicated effective CNS targeting of SQVM via intranasal route. Gamma scintigraphy imaging of the rat brain conclusively demonstrated transport of drug in the CNS at larger extent after intranasal administration as NE.

SIMILAR ARTICLES

PubMed Epub, 2016 Jun 28:

HYDROGEL NANOPARTICLES AND NANOCOMPOSITES FOR NASAL DRUG/VACCINE DELIVERY

Sara Salatin  1   2 Jaleh Barar  1   3 Mohammad Barzegar-Jalali  3 Khosro Adibkia  3   4 Mitra Alami Milani  2   4 Mitra Jelvehgari  5   6 Affiliations Expand

Affiliations

  • 1 Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Science, Tabriz, Iran.
  • 2 Student Research Committee, Tabriz University of Medical Science, Tabriz, Iran.
  • 3 Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Mailbox 51664, Tabriz, Iran.
  • 4 Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
  • 5 Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Mailbox 51664, Tabriz, Iran. mitra_jelvehgari@yahoo.com.
  • 6 Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. mitra_jelvehgari@yahoo.com.

ABSTRACT

Over the past few years, nasal drug delivery has attracted more and more attentions, and been recognized as the most promising alternative route for the systemic medication of drugs limited to intravenous administration. Many experiments in animal models have shown that nanoscale carriers have the ability to enhance the nasal delivery of peptide/protein drugs and vaccines compared to the conventional drug solution formulations. However, the rapid mucociliary clearance of the drug-loaded nanoparticles can cause a reduction in bioavailability percentage after intranasal administration. Thus, research efforts have considerably been directed towards the development of hydrogel nanosystems which have mucoadhesive properties in order to maximize the residence time, and hence increase the period of contact with the nasal mucosa and enhance the drug absorption. It is most certain that the high viscosity of hydrogel-based nanosystems can efficiently offer this mucoadhesive property. This update review discusses the possible benefits of using hydrogel polymer-based nanoparticles and hydrogel nanocomposites for drug/vaccine delivery through the intranasal administration.

Keywords: Brain; Hydrogel; Nanoparticles; Nasal delivery; Vaccine.

SIMILAR ARTICLES

Yes, they CAN vaccinate us through nasal test swabs AND target the brain

NTS Notes:  Honestly, why should anyone be in the least bit shocked by all this?

I had heard rumblings for months now that the nasal swabs were in fact the 'vaccines' and I could not find anything that properly provided the proof that this was the truth, until now..

And honestly when we consider how truly evil and diabolical these pricks really are running this entire scam, this all makes perfect sense....

Keep this in mind the next time some asshole requests you be 'tested' for this non-existent 'deadly virus'.... Never ever go to those testing facilities, and refuse the test, period!

More to come

NTS

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